depends 
normally, those should be safe, but 5 red indidcates that updating kernel could affect graphics, drivers, etc. that could make your system unstable, so finding a good stable recent kernel that fits your selection of hardware is key, and if it runs fine, its the users risk to update, which usually should fix problems on newer hardware, but could also have regressions.
normally, those should be safe, but 5 red indidcates that updating kernel could affect graphics, drivers, etc. that could make your system unstable, so finding a good stable recent kernel that fits your selection of hardware is key, and if it runs fine, its the users risk to update, which usually should fix problems on newer hardware, but could also have regressions.